Understanding the neural basis of human brain function requires knowledge about the spatial and temporal aspects of information processing. Functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) represent complementary brain imaging techniques in terms of their spatial and temporal resolution in the examination of sensory and cognitive processes underlying brain function. In this project, we are initially interested in tackling important technical and scientific questions related to the acquisition, validation and analysis of simultaneous fMRI and EEG data. For example, EEG data acquired in the scanner is contaminated by a number of artifacts which can significantly reduce the quality of the data. To solve this problem, we propose to develop, test and validate procedures for artifact reduction in simultaneous EEG-fMRI acquisition at 3T. We also plan to use continuous, single-trial, EEGs as well as averaged EEGs to validate the effectiveness of the proposed artifact removal procedures for detecting task-relevant brain activations. .Related Publications Menon, V. & Crottaz-Herbette, S. Combined EEG and fMRI studies of human brain function. Int Rev Neurobiol 66, 291-321 (2005). Abstract     PDF Menon, V. et al. Spatio-temporal correlations in human gamma band electrocorticograms. Electroencephalogr Clin Neurophysiol 98, 89-102 (1996). Abstract     PDF Menon, V., Ford, J. M., Lim, K. O., Glover, G. H. & Pfefferbaum, A. Combined event-related fMRI and EEG evidence for temporal-parietal cortex activation during target detection. Neuroreport 8, 3029-37 (1997). Abstract     PDF Srivastava, G., Crottaz-Herbette, S., Lau, K. M., Glover, G. H. & Menon, V. ICA-based procedures for removing ballistocardiogram artifacts from EEG data acquired in the MRI scanner. Neuroimage 24, 50-60 (2005). Abstract      PDF